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Diabetes insipidus is rare in cats and is characterized by excessive drinking and the production of enormous volumes of extremely dilute urine. Despite drinking large volumes of water, the cat can become dehydrated from urinating so much. Increased drinking and urination are common signs of several other health conditions, so it is essential that several diagnostic tests be performed to diagnose diabetes insipidus. While the condition is rarely curable, it is usually successfully controlled.
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Diabetes insipidus results in excessive drinking and urination. As many conditions cause these signs, a number of diagnostic tests including bloodwork and urinalysis need to be performed to rule out other causes. After more common causes are ruled out, a modified water deprivation test can confirm disease and an MRI or therapeutic trial can be performed. Diabetes insipidus results from reduced production of ADH from the brain or reduced sensitivity to ADH in the kidney. Treatment depends on the cause of the disease either replacing the lack of ADH with a synthetic replacement or using a hydrochlorothiazide and a low salt diet to decrease urine production.
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Diabetes mellitus is an inability to regulate blood glucose caused by a loss of insulin production (Type I) or inadequate insulin supply or resistance (Type II). Dogs need insulin injections to manage diabetes. Sometimes special diets may help manage the disease. Response to insulin needs to be monitored to ensure adequate dosing and to avoid hypoglycemia caused by insulin overdose. Blood glucose curves are most commonly used for this including: in-clinic blood glucose curves, home glucose curves with hand-held glucometers and continuous glucose monitoring systems. Urine glucose testing and fructosamine testing may also be used to manage the disease. Hypoglycemia is the consequence of administering too much insulin compared to the amount of food ingested. Signs can range from lethargy to seizures and coma. It can be managed acutely with administration of sugar syrup to the gums but more severely affected dogs will need IV dextrose solutions.
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Cats with diabetes have the potential to go into remission where they may no longer need to receive insulin. Factors that can affect the likelihood of remission include the type of insulin given, your cat's diet, and how long your cat has been diabetic. It is important to recognize the signs of hypoglycemia, as they may be your first indication of remission.
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Diarrhea is a symptom of an underlying problem that may be minor or very serious. Some cases may resolve on their own or with minimal treatment, while other cases require in-depth diagnostic testing and more aggressive treatment to address the underlying condition. The possible causes, diagnostic tests, and treatment protocols for diarrhea in cats are numerous and they are explained in this handout.
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Diarrhea is a symptom of an underlying problem that may be minor or very serious. Some cases may resolve on their own or with minimal treatment, while other cases require in-depth diagnostic testing and more aggressive treatment to address the underlying condition. The possible causes, diagnostic tests, and treatment protocols for diarrhea in dogs are numerous and are explained in this handout.
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If your cat is having diarrhea, please complete this questionnaire as accurately as possible before your appointment. This information will be very helpful to your veterinarian in determining the cause of diarrhea.
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If your dog is having diarrhea, please complete this questionnaire as accurately as possible before your appointment. This information will be very helpful to your veterinarian in determining the cause of diarrhea.
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Discoid Lupus Erythematosus (DLE) is an autoimmune condition that causes skin sloughing particularly around the nose causing scabbing and erosions that can become infected with bacteria. It can also affect the ear flaps, genitals and rarely spread through the entire body. DLE is diagnosed by submitting skin biopsies of affected areas for histopathological analysis. As well as antibiotics to treat secondary bacterial infections, treatment involves suppression of the immune system including tacrolimus or steroid ointments/creams applied to the affected area. Some dogs will need tetracycline and niacinamide or stronger anti-inflammatories such as cyclosporine or corticosteroids. These treatments can be weaned once lesions resolve but flare-ups will likely occur, needing rechecks and repeat therapy. Sun exposure must be minimized as UV light can worsen the disease. If untreated, lesions can develop into squamous cell carcinoma.
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Discospondylitis is a bacterial or fungal infection of the intervertebral disks and the adjacent vertebral bones. It primarily affects dogs, though rarely can affect cats. It affects large breed dogs more often and generally starts clinically as back pain. The diagnosis and treatment of this condition are outlined in this handout.
